kjmhoffman

-only daughter of John f Howell principal engineer at the Pinellas plant

Archive for the tag “Radiation therapy”

tREATMENT


tREATMENT

The same physical qualities that make radiation dangerous to humans make it a valuable therapeutic agent — it can kill cancerous cells as well as healthy ones. The therapeutic challenge is to focus the right amount of the right kind of radiation on the diseased cells, while sparing the surrounding healthy tissue. Post-World War II research, much of which involved radionuclides, helped make radiation treatments more locally precise and the dosage safer and more accurate.


Treament panel.

Advertisement for General Electric Company, “Atomic Weapons Join War on Cancer!” Published in Newsweek, October 11, 1954.

This advertisement, which pictures a super- voltage x-ray machine, demonstrates the popularity of the “atomic” label in the mid-1950s. Although x-rays were used to treat cancer, as were the radioisotopes of cobalt and cesium, high- energy x-ray machines were first developed before World War II and owed little to the nation’s development of atomic energy.

Patients entering “Uranium Tunnel”, Lone Rock, Wisconsin, 1954.

The therapeutic effects of radioactivity were applied outside the scientific community as well. In 1954, Lone Rock farmer Kenneth Crook opened a storefront and began charging the public $1.00 an hour to sit on uranium-filled cushions. Although Crook claimed his popular “uranium tunnel” was meant only to entertain and educate, the State of Wisconsin charged him with practicing medicine without a license and closed all the state’s uranium “cures” in 1955.

Cobalt-60 radiotherapy machine Used at Wisconsin General Hospital, Madison, ca. 1960.

Originally developed in 1951, the telecobalt machine used the high-energy gamma rays emitted by cobalt-60 to treat cancer. Cobalt-60 machines were able to reach deeper tumors with less skin dosage than standard x-ray machines. Courtesy of Department of Medical Physics, University of Wisconsin-Madison.

Professor John Cameron, holding pellet of lithium fluoride, University of Wisconsin, Madison, 1962.

Cameron helped develop thermoluminescent dosimetry, a technique for measuring therapeutic doses of radiation. A small pellet of lithium fluoride, which absorbs energy from radiation and emits it as visible light when later heated, is placed next to an area to be treated with radiation. By measuring the amount of light given off by the pellet, doctors can tell exactly how much radiation the patient has received at the intended point of treatment. Courtesy of the University of Wisconsin-Madison Archives.


Treament panel
(close-up).

R-meter Made by Victoreen Instrument Company, Cleveland, Ohio, 1947.

This instrument measured the intensity of radiation from high-energy x-ray or cobalt-60 radiotherapy machines so that accurate doses of radiation could be administered. Courtesy of Department of Medical Physics, University of Wisconsin-Madison.

Set of collimators, ca. 1955.

A collimator is a device that defines and limits a field of radiation. These metal caps, each with an opening of a different size and shape, were placed over a small metal cylinder of radioactive strontium-90, which was then applied directly to a diseased eyeball for the treatment of tumors. Courtesy of Department of Medical Physics, University of Wisconsin-Madison.

http://www.wisconsinhistory.org/museum/atomic/hope.asp

Malignant fibrous histiocystoma- linked to genetics, radiation treatment and inherited diseases.


Malignant fibrous histiocystoma

DISEASE INFORMATION

Overview

A malignant fibrous histiocytoma is a type of cancerous tumor that can start in either bone or, most often, in the soft tissues that connect, support or surround organs and other body parts. Dana-Farber/Children’s Hospital Cancer Center provides comprehensive medical and surgical care for children and adolescents with benign or malignant bone and soft tissue tumors.

  • It’s a painless mass that most often turns up in the extremities, although it can occur anywhere in the body.
  • It most commonly spreads (metastasizes) to the lungs, but can also invade the lymph nodes and bone.
  • The cause is unknown but has been linked to genetics, radiation treatment and inherited diseases.
  • It’s among the most common types of soft tissue tumors found in adults but is rarely found in children.
  • Treatment may include surgery along with radiation and/or chemotherapy.
  • The tumor can come back.

How Dana-Farber/Children’s Hospital Cancer Center approaches malignant fibrous histiocytoma

Our multidisciplinary approach to care ensures in-depth discussion of each case and personalized treatment plans for every patient. We integrate expertise from the following specialists at Dana-Farber Cancer Institute and Children’s Hospital Boston.

  • pediatric oncologists, surgical oncologists and radiation oncologists
  • pediatric experts from every medical subspecialty, such as orthopedics, ophthalmology, physical therapy and radiology, among others
  • highly skilled and experienced pediatric oncology nurses
  • child life specialists, psychologists, social workers and resource specialists who provide supportive care before, during and after treatment

We are conducting numerous research studies to help better understand and treatsoft tissue and bone sarcomas.

malignant fibrous histiocytoma cause of death of john f howell


Computed tomogram of the abdomen prior to init...

Computed tomogram of the abdomen prior to initiation of cytotoxic chemotherapy demonstrating right-sided abdominal wall soft tissue mass (16 × 9 cm) (arrow), and mesenteric soft tissue mass (7 × 5 cm). (Photo credit: Wikipedia)

English: Soft tissue and bone filtered CT images.

English: Soft tissue and bone filtered CT images. (Photo credit: Wikipedia)

English: Intermed. mag. Image:Paget disease of...

English: Intermed. mag. Image:Paget disease of bone – high mag.jpg (Photo credit: Wikipedia)

Granular cell tumor

Granular cell tumor (Photo credit: Pulmonary Pathology)

Malignant fibrous histiocystoma

DISEASE INFORMATION

In-Depth

What is malignant fibrous histiocytoma?

A malignant fibrous histiocytoma is a type of cancerous tumor that can start in either bone or, most often, in the soft tissues that connect, support or surround organs and other body parts. It’s a painless mass that most often turns up in the extremities, although it can occur anywhere in the body. It most commonly spreads (metastasizes) to the lungs, but can also invade the lymph nodes and bone.

What causes malignant fibrous histiocytoma?

The exact cause of malignant fibrous histiocytoma is not entirely understood, however, studies have indicated that genetics may play a role. In addition:

Is malignant fibrous histiocytoma common?

While it’s among the most common types of soft tissue tumors found in adults, it is rarely found in children. It makes up only a tiny percentage of all soft tissue sarcomas, which as a group account for only 1 percent of new cancer cases in children each year.

What are the symptoms of malignant fibrous histiocytoma?

Because soft tissue sarcomas affect tissue that is elastic and easily moved, a tumor may exist for a long time before being discovered, growing large and pushing aside surrounding tissue. Symptoms vary greatly with the size, location and spread of the tumor, but may include:

  • painless swelling or mass anywhere on the body
  • pain or soreness caused by compressed nerves or muscles
  • limping or other difficulty using the legs, feet, arms or hands

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